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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b463dbc4019b09bcd6e6da48a2aa970f13ad3e59b20d89b5185444d89ab735a' 
  AND token = '3LQansiVXy8UIBtkgDSkgYlxhsT/z9OczbvI+yp2Hlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}