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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8527dd4bd7d11370ce8683015d46923fd4f02c5011d03dc1726065519f2783' 
  AND token = 'UyXqv6YgRBgKMe6/+hHEIIQiYchAdF9EOmjl76e454w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}