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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9371e9e5b38803b2314b4d768539e1ccbd5e2ca7376cff37d038f2d213c816' 
  AND token = '6KrpHSFUS3uEDeNmTibzrYlCZ49NpaZgQJgIYYOvpHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}