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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81e16a141572641c0230a4bd14aafb49251fc01c468ac1a1a3515e865f16471' 
  AND token = 'EXRzt7WnU0iophtbQzdxZWt/nzEsaHPRwP78lf4qJ4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}