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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83c0d788d3ac3399f0ccbe7dbde50d5dbb19b144e8a202299b81e5e7846cad80' 
  AND token = 'TqaIH9Wpcv5XSxd0or0PePtIp+E2taadBpaAVhTM9RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}