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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66db9d5780a7699b08b09894644d16eaba0b3ba53d2a1fd15be4f19a6a629d3' 
  AND token = '0BTmf4QSyKoMzWhbnCV6B+1h9w2RSg+WPw85Z+pT29w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}