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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277f7bce9096f3b4519cecd7d259db687eed2a496d0f7551df119f1a8d77cb19' 
  AND token = 'vo4lnbG+HeGIsW/7Ptd8Jqdt8YOizQaDJdDGB5nTw4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}