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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c074955e5a15e53fd0db16a368e883dcbf3542d7a937dccd81a7cc2eb82e84e7' 
  AND token = 'JolEjq4Ujp6ahMmzoCnjIWIrbR+vWM8sZTYa/WcUe3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}