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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ce44b3a1e380821f9275654f0181ade5580cecd5560d451937dde8516f3f41b' 
  AND token = 'vXqsuy3XV9Z47s0RgTzKiM4u61XSZvi1zdFA4+xjTHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}