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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a74c7d81e0748f2ed756f392e57a09c429a9d05e51985b9a3f52b298d5593a1' 
  AND token = 'TzEc/SYeeWuLKFkan8sylct0ZCTj6TDl62FJv1EuAZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}