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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '852b6d43cb1b9ba11b9cdfe4308b7ce5f237a8c51f7e100ade964fe544d12dc7' 
  AND token = 'JzSUuMIz0D362d4fe577TlnvY2EfEMJ1EJ5VSSua/9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}