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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680779cf46234e669e6617583ade7ffd42ef398d023462eaa013cbb3cf072538' 
  AND token = 'J1NptxoKzeeER2dOpp/05p7SSIHPrC3f+TsVjrsfaIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}