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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c6faca15d12de673a696f5aebcd0456158527c5f5b7a45865570c738f83205' 
  AND token = '6jCYaYobi1kT/wUHx0sbqPYRjRQ42e2AKNGpT0ZK39c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}