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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf09d63d4f3c80243ba18cd025f678bc3af99dce6555cc5cc697708abc443ebf' 
  AND token = 'tDco8Y1JA7y+bASmLRRJ3EiFZx8y6jqRA6+O5ooz9W0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}