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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1757b30680e03da72a749348e74bdf985e72cbbd335aef26e04e43b342e2cfac' 
  AND token = 'dLgrVTSqGQPEHdDoydGMXwmYWI3RV5mi/ESKRy+3dhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}