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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9224938f008df8ee512548ee5194255aed963d4bd140195703e6507265074f48' 
  AND token = '3t8EQSZIx4vn9fl/BFF6GJSWG8BiG2iOv0mOTVAAteo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}