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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433da1647ff5ae8534f079802a6d8f678d2abfaa14a572c9d64e11ed183938c8' 
  AND token = 'ozf4AVb+D+Qe3c/vx3XPz2J5KkS3QIT6A40q8QwtpvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}