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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6105471ad7410319ac32b86b3b8d80a5e604b69cafcdba4aeed32b608248ee6' 
  AND token = 'Qx2IE/mQCw5XtCbk0KqEpYBULfchs0we1tzOh51CDt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}