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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d2df2e3a3cff48932d0fe0eaa5a63d90440bd915c9d0ec6f0d422a6f47911c' 
  AND token = 'dCYVYHGf3SQ/inO2r3qRmX+9hqcmkX5MjeOn3gyQPH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}