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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cff1fc2dc43999903227e72cfe55e3a863b03d1834c8c5d1c2a675d0b22e3b8b' 
  AND token = 'SAWXAjazEvWmSk3hTSYZJUqvY5nIW5Eq6WVlJMILloQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}