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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66e28785febb53cd6ffa0b6e4a7f87331c16fe0c0c8772752fc8c9d0a932189' 
  AND token = '0waQ6ygVC8H0Wv768Tn30ZJsk9RpoSGffo0+jkTvdGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}