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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee36320e6953960ff886e679843c2e937f2c677e44bfd3806e779f6474600243' 
  AND token = 'lAu4IQn/SztQwRyBGRBbnKRwjegxwhjkAlnfFsN61rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}