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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c25aaab50bf0e81d37d9a718e94d2f51f04920a54fc81704da59f4831585c1' 
  AND token = 'Asvz188u5eDlz2UTUGyBnoVeeqo/kCJ2wJhXRacbA4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}