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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f36f01d78296ae26ee737f76a07891391321aea35195c6f5504c5b215447009c' 
  AND token = 'IDkJa5arbU5DB55Ot57zsO4p14zEgelfxG0vL43nWK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}