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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4a26fec60bebd42af2aa75c70014da6a91ea740bf01a9d48e47bcd57a97b287' 
  AND token = 'H/p1VzNcD7coL3+MtMKnwmXmAKAVHuBpf8I8+7yXzzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}