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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85a45511387f4cea00404ef6963c2b65bd4f7cc005c7026baa8dc869b8c8cce8' 
  AND token = 'D1Wu1kTvon4R9Aglfygt5B7lJgUJsYkedoIfpaVNRAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}