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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '323ab8168bb837e57840c5262a865efe21178d4e66d5cf6d84bd11c4f3e84852' 
  AND token = 'EEbd8N9BlvDMsl+pQB/KNvg5KqZ5rl/eLyrcPbLsKKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}