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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406d210aca36b7bf7fb856c6e19cc73153293d8593c7ba557e04ac20f842b166' 
  AND token = 'FCl8+7PD3f7T6K/PEdDI7LASZ3JOe6s+x9P1QdEP2Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}