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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab43616a1765be5b4ed61270965331e24a9fd2f1af6e3d23869ba7c6cc3657bf' 
  AND token = 'zuwAS/MKKfPE5vhZ9lQfklTPoJY5286MSIYHuuyZtoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}