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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0cc479b47ae911c978558c3d46397d422e745e038b4886a520b4c28a9b8196' 
  AND token = 'SXbmS6//s5+ROvLaaGIq0QzUEfZZ2s0gD1kvmqYkIqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}