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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e567eeeae0b4cbaaba1ad3a9a2be081e4351e0fde790c68829e4331a4c51e60' 
  AND token = 'hWTR52aK7bJFRQ8IvTbg6I/rv0cnVLFhzJvghIrOGXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}