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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58ec6332340986faec3fe57f6be267c427b92be17f0eb3bdd441e8b4ddc8a907' 
  AND token = 'DE8LRAH1p/xMHrfFpZo1OO4cUV7SfThfEQCDfH2KxLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}