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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '467f0a3ee98d47720eb0b4cdc91e5765dd5d5dc4917a4714a462f5e232fe78fb' 
  AND token = 'Re2uTkCoNeETel/9z3YUOt25jpKIp10DZU5NH/DkiBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}