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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9e07522503d801979b2ccb8fea0fbe9148d8e72c7455beadb242e6d7ad1f316' 
  AND token = '2ZJ1ClUpxPQs+aRt8uEXDSK+DyVO5dxpP6LaabIerz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}