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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59dc82675c7c1812f9b6b3a8ca3b2b9051031d0cbf21f072a4f4fba13d52c099' 
  AND token = 'laA8rD8I5LStl7PYUwYWSkmTScjtk9GO4qkKoQUb3bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}