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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14efcd6fd9c4d70c372e86c8d467e201d851b8dd7b6409209c731c1347e0c434' 
  AND token = '+gDirHe0Ln96uGgyUEOpCxqhzlP75AU0L730CPqVaqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}