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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db886e44b5a3dd003fec5491ad351a38a94836f7e02243e4a8d4129c53b0c183' 
  AND token = 'tUnK9dTEDuL/+dlx9Mn6Mhzkn+rsn+FXd/FeJV2lBZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}