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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '963045d521df8d6f9aba30dff4ebcceffb26f81b12fce3b6385c450a8d6dad00' 
  AND token = 'xciICoNgPDG1Y+NT7tH7rUfOChowTd4l+HnhsQ1RMis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}