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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ca2050acc26d8460c6f73d27f09251009b401bd7f2e9070046c4b903a42bd8' 
  AND token = 'wSDz50NeyJpjzbYfin1bUf77tPJhCLD6sN5wdhsPX3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}