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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e88c741e3ab21668d917349ae20aef1f1c47cc6ccfbbbe74ec506163c64effd0' 
  AND token = 'Quh56Tf124h+WyH3WLrdKAdfOKK00AhVQuzzpvL/CkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}