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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00454a6ea8033170f54dc2c6c3d3de10d7c6a5564f01d18acf9730b4b3a9f1f8' 
  AND token = 'dWWSDu7Yzj7k1cgbGl9iA6mncVUvIhjc2V2ZBvWq5c0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}