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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea7bf91f178e324c2de9dee70f9871ba6da020893ff0a97d8f1189e93bf7884' 
  AND token = '6/P2QswZMQ0plXerngq39Z2wcn+38tybWhM8QO5y/NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}