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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac397bd740b06338baca148357770364aa04bc267cc0c348f5920fd71815bf7' 
  AND token = 'xzhm/VNvIwT621Lx49Itp5/eGftY3sKdY4s21kcH+Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}