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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aaed3f4ee759604428a727e68b32615cb7493ae6374766640e2f8607ec13d5a' 
  AND token = 'b49164lxPAl//KsChdBQgr2ckVHe4/3xq+q0MIPgb7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}