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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c52f4df19acc22f2de751ce116bff1a60c198307c11a647ca68ba8ba53640ffb' 
  AND token = 'zd6XJoC15dIwKL3NsHRw03VwGAEbF5cvbgOT9MuzlXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}