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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1e5c3c8fa62689761f852af7adc7b5dc6d35cdf1511fc713023aee18e2f7f0' 
  AND token = 'fe4sA5UEiUU/+nJ/qV7+LnhSeNXYsUdqgmb3Gh6bSEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}