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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa52e318eec5c40a86a9bccf32b71fe428843dc272479d6998f84295b409672' 
  AND token = 'sRP3Gh7UfSsaolXRWn4/fz/FtAo5l/8PKNgPOFLqz2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}