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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95da08f77bf68d43d232399c3fc72485ee07edf515fd20f32fc073416818a4f5' 
  AND token = 'kIa36D+3x2IIEzauCA8NTWCGwTttoMXF6f9iKAKRZ4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}