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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cacc22895e9e42661d233efbe08c10d600994ed3fb2e518aea7bc04f22585412' 
  AND token = '1PMlp+RAwntl6sopTQ8hjTKKCvixYxxR2f/vp5GQObc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}