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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8260be59c2835e110ea74f79b6761acd1111bf5b2f019c0d95dd8eb78fbb7a29' 
  AND token = 'oSgupLKByKLk0vT80hSSmo1X39cmjIXZvx0Rh7ZQSuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}